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    Ipamorelin

    What is Ipamorelin?


    Ipamorelin is one of the latest and greatest peptides in the growth factor family. It is one of the most researched of all peptides and is deemed one of the safest.

    It's benefits are;

    • Decreased body fat
    • Improved sleep
    • improved muscle mass
    • Increased collagen production.

     BIOV8 uses only premium pharmaceutical grade in all of our products.

    Snapshot

    Ipamorelin is one of the latest and greatest peptides in the growth factor family. Deemed one of the safest GHRP's, Ipamorelin is a selective growth hormone (GH) Secretagogue and Ghrelin receptor agonist.

    This peptide generates similar increases in growth hormone secretion, but without the appetite stimulation and increase in cortisol, acetylcholine, prolactin, and aldosterone seen with other peptides in its class. 

    Ipamorelin is a pentapeptide – a hormone composed of five amino acids – that emulates the natural growth hormone release found in the human body.

    In essence, it’s a growth hormone releasing peptide (GHRP), an analogue of ghrelin, the ‘hunger’ hormone known for its stimulation of appetite. Ipamorelin binds to the ghrelin receptor, inducing the release of growth hormone. This increases the number of GH-releasing cells (somatotrophs) in each pulse of growth hormone, which is done by suppressing somatostatin, a hormone that inhibits GH production.

    Much like other peptides, ipamorelin stimulates growth hormone release in a similar manner to the growth hormone-releasing hormone (GHRH), which facilitates many of the benefits for which patients seek it out.

    Ipamorelin acts as a method of growth hormone (GH) restoration. When used as a therapy, it stimulates the pituitary gland, thereby producing a greater amount of endogenous growth hormone in the human body. Rather than artificially injecting yourself with artificial growth hormone, ipamorelin allows the body to naturally produce said hormone.

     

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    How Does Ipamorelin work?

    When Ipamorelin is administered, the hormone goes to work, stimulating the pituitary gland to release higher levels of human growth hormone in the body. From there, cells mobilize, traveling to the muscles of the body to facilitate muscle growth and development.

    Potential benefits 
    • Decreased body fat
    • Increased collagen production
    • Increased lean muscle mass
    • Improved sleep
    • Increased cellular repair and & Regeneration
    • Increased IGF-1
    • Increases bone mineral content
    • Counteracts glucocorticoid catabolic effects
    • Less appetite stimulation than GHRP-6
    • Less release of cortisol, prolactin, and aldosterone

    Ipamorelin has been shown to be highly potent and has also demonstrated good safety and tolerability in human clinical studies. 

    Research has shown that Ipamorelin is growth hormone specific, which means that the pituitary hormones (such as cortisol are unaffected). 

    Ipamorelin may be one of the best alternatives available to HGH therapy.

    As an added perk, it does not promote increased production of the enzyme ghrelin, which stimulates hunger. This means that it will not make you hungry, due to Ipamorelin's ability to control points of gastric, appetite, and growth motility.

    Another very significant positive difference is that Ipamorelin does not display a capacity to significantly boost levels of cortisol, which can affect the body in unwanted ways. Patients on other types of secretagogue therapies have reported jitters, cold sweats or nervousness because therapy’s overall impact on cortisol levels. 

    DOSAGE

    Suggest dosage:  0.10ml per day 5 days out of 7 (10 weeks supply).

    Transdermal Option: 200mcg/mL x 50mL – Apply 1mL daily 5 days out of 7 (10 weeks supply).

    Generally, the recommended dose for ipamorelin is 200 to 300 mcg per day. Most ipamorelin treatments last from eight to twelve weeks, though they can sometimes last longer, and a single dose of ipamorelin can last up to three hours; go beyond these doses, however, and you can create potentially disfiguring cartilage and bone growth, which is why it’s always good to consult a medical professional.

    When administered correctly, ipamorelin can work in a “pulsatile fashion,” working with the natural chemistry of the body without using up the existing reserves of growth hormone already present.

    The length of an ipamorelin regimen is generally up to the patient, but certain lengths of therapy are used for certain purposes.

    Most take ipamorelin for a short period of three to six months, often for its fat loss benefits and to improve their body composition.

    However, others might use ipamorelin peptide therapy for longer periods of time (six to twelve months) to take advantage of its anti-aging effects, such as greater body composition, improved sleep, improved cognition and more.

     

    Potential Side Effects
    • Redness, itchiness, or irritation at the injection site, which usually is temporary
    • Increased appetite/hunger (though this can also be due to the net effect of a boosted metabolism and more muscle mass gains)
    • Dry mouth
    • Nausea
    • Increased weight (typically due to muscle mass gains and body fat loss, since muscle weighs more than fat)
    Technical overview and history

    Sequence  Aib-His-D-2-Nal-D-Phe-Lys-NH2.

    Description Ipamorelin Synthetic is a single, non-glycosylated polypeptide chain containing 4 amino acids, having a molecular mass of 711.85 Dalton and a Molecular formula of C38H49N9O5.

    Beware of Counterfeit

    The internet is full of counterfeit peptides and products of inferior quality. BIOV8 is committed to providing only the highest quality pharmaceutical  grade products and can provide proof of purity and sterility results. BIOV8 peptides are only prescribed by one of our qualified licensed practitioners which is required by law.

     

    *** Please note. All injectables come with syringes.  If you're purchasing a vial we recommend purchasing a sharpies box for safe disposal. Buy as a single unit vial or in a bundle***